This month we reflect on the exciting AlphaFold2 breakthrough by DeepMind. We've also got new coronavirus puzzles just in time for the new year. Watch our latest lab report on YouTube now.

NEWS
- AlphaFold2 and protein structure prediction

PUZZLE UPDATES
- MERS-CoV binder design
- Two-sided interface design
- More designable linker puzzles

DESIGN OF THE MONTH
- A designed linker solution, by nspc, with a substantial core that spans the entire protein. See for yourself in the Design of the Month sandbox puzzle.