puzzle picture
1921: Designable Linker: Coronavirus Spike Binder
Status: Closed

Groups

RankGroupScorePoints
1Go Science25,167100
2Gargleblasters25,13871
3Contenders25,02549
4Anthropic Dreams24,94633
5Beta Folders24,27222
6Void Crushers23,68314
7L'Alliance Francophone23,0778
8BOINC@Poland22,8285
9Marvin's bunch22,4283
10Team China21,7102
11Russian team19,6491
12FoldIt@Netherlands19,2631
13Italiani Al Lavoro14,7291
14Team Canada13,8141
15FRS 004-18 & 004-28 UC Davis, 2020031,7501
16Foldit Staff1,7501


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neilpg628's picture
User offline. Last seen 1 day 14 hours ago. Offline
Joined: 08/01/2019
Groups: Foldit Staff
Objectives

Residue Count (max +550)
Penalizes extra residues inserted beyond the starting 240, at a cost of 55 points per residue. Players may use up to 250 residues in total.

Core Existence (max +2400)
Ensures that at least 35 percent of residues are buried in the core of the monomer unit.

Interaction Energy (max +500)
Monitors that all large PHE, TYR, and TRP residues are scoring well.

SS Design (max +500)
Prohibits CYS residues. Penalizes GLY, ALA residues in sheets. Penalizes GLY, ALA, SER, THR in helices.

Ideal Loops (max +500)
Penalizes any loop region that does not match one of the Building Blocks in the Blueprint tool. Use "Auto Structures" to see which regions of your protein count as loops.

Joined: 12/06/2008
Groups: Contenders
Constant crashing?

Anyone else experiencing constant crashing of the game while playing this puzzle? There is no one action I do that causes the crash.

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, RosettaCommons