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1921: Designable Linker: Coronavirus Spike Binder
Status: Closed
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Groups
1 | Go Science | 25,167 | 100 |
2 | Gargleblasters | 25,138 | 71 |
3 | Contenders | 25,025 | 49 |
4 | Anthropic Dreams | 24,946 | 33 |
5 | Beta Folders | 24,272 | 22 |
6 | Void Crushers | 23,683 | 14 |
7 | L'Alliance Francophone | 23,077 | 8 |
8 | BOINC@Poland | 22,828 | 5 |
9 | Marvin's bunch | 22,428 | 3 |
10 | Team China | 21,710 | 2 |
11 | Russian team | 19,649 | 1 |
12 | FoldIt@Netherlands | 19,263 | 1 |
13 | Italiani Al Lavoro | 14,729 | 1 |
14 | Team Canada | 13,814 | 1 |
15 | FRS 004-18 & 004-28 UC Davis, 202003 | 1,750 | 1 |
16 | Foldit Staff | 1,750 | 1 |
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Comments
Residue Count (max +550)
Penalizes extra residues inserted beyond the starting 240, at a cost of 55 points per residue. Players may use up to 250 residues in total.
Core Existence (max +2400)
Ensures that at least 35 percent of residues are buried in the core of the monomer unit.
Interaction Energy (max +500)
Monitors that all large PHE, TYR, and TRP residues are scoring well.
SS Design (max +500)
Prohibits CYS residues. Penalizes GLY, ALA residues in sheets. Penalizes GLY, ALA, SER, THR in helices.
Ideal Loops (max +500)
Penalizes any loop region that does not match one of the Building Blocks in the Blueprint tool. Use "Auto Structures" to see which regions of your protein count as loops.