bkoep's picture
User offline. Last seen 17 hours 48 min ago. Offline
Joined: 11/15/2012
Groups: Foldit Staff
Objectives

Residue Count (max +1100)
Penalizes added residues at a cost of 55 pts per residue. Players may add up to 20 residues, for a total of 200.

Buried Unsats (max +500)
Penalizes polar atoms that cannot make hydrogen bonds, -150 points per atom (not including symmetric copies).

Core Existence: Total (max +5000)
Ensures that at least 25% of residues are buried in the core of the entire solution.

Interaction Energy (max +500)
Monitors that all large PHE, TYR, and TRP residues are scoring well.

SS Design (max +500)
Penalizes all CYS residues. Penalizes GLY, ALA residues in sheets. Penalizes GLY, SER, THR in helices.

Ideal Loops (max +500)
Penalizes any loop region that does not match one of the Building Blocks in the Blueprint tool. Use "Auto Structures" to see which regions of your protein count as loops.

Joined: 09/29/2016
Groups: Gargleblasters
...

ATTENTION PLAYERS

1903 has a slight bug currently, which causes Blueprints to move the Locked Helices on Segments 1-90 bundle. I've let bkoep know, BUT in the meantime...

HERE IS WHAT YOU NEED TO DO IN ORDER TO PLAY
(1) Reset your puzzle
(2) Open View Options
(3) Enable: 'Show backbone pins'
(4) Rotate camera to so you can see where the end of the first-chains Loops end (Segment 90),
(5) Click on the Pin at the end

This will cause the pin to jump to where it is supposed to be.
NOW you can go about playing the puzzle and using Blueprints.
:)

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, RosettaCommons