|
|
|
1901: Coronavirus Anti-inflammatory Design: Round 14
Status: Closed
|
Soloists
|
| 1 | Joanna_H 46 1603 | Gargleblasters | 12,233 | 100 | | 2 | Bruno Kestemont 3 3 | Go Science | 12,230 | 97 | | 3 | ichwilldiesennamen 22 10 | Go Science | 12,181 | 94 | | 4 | malphis 46 1603 | | 12,176 | 91 | | 5 | grogar7 46 19 | Anthropic Dreams | 12,172 | 89 | | 6 | mirp 46 236 | Go Science | 12,118 | 86 | | 7 | jawz101 46 554 | | 12,109 | 83 | | 8 | Galaxie 1 2 | Anthropic Dreams | 12,077 | 78 | | 9 | NinjaGreg 37 15 | Go Science | 12,024 | 75 | | 10 | BootsMcGraw 10 8 | Contenders | 11,999 | 73 | | 11 | OWM3 46 1603 | Gargleblasters | 11,997 | 71 | | 12 | Mike Lewis 46 1603 | Gargleblasters | 11,994 | 68 | | 13 | dcrwheeler 46 4 | | 11,993 | 66 | | 14 | LociOiling 2 1 | Beta Folders | 11,982 | 64 | | 15 | spvincent 29 11 | Contenders | 11,981 | 62 | | 16 | Vinara 46 57 | | 11,978 | 60 | | 17 | robgee 7 6 | Anthropic Dreams | 11,950 | 58 | | 18 | John McLeod 46 1603 | Anthropic Dreams | 11,945 | 56 | | 19 | ZeroLeak7 46 95 | Go Science | 11,934 | 54 | | 20 | ucad 46 43 | | 11,929 | 52 | | 21 | sgeldhof 46 39 | | 11,921 | 50 | | 22 | justjustin 46 1603 | Anthropic Dreams | 11,911 | 48 | | 23 | Mike Cassidy 46 59 | Void Crushers | 11,889 | 47 | | 24 | Philzord 46 1603 | Go Science | 11,881 | 45 | | 25 | Skippysk8s 34 28 | Gargleblasters | 11,875 | 43 | Need this puzzle? Log in to download.
Comments
|
|
|
|
|
|
|
|
|
|
|
|
DDG Score (max +0)
The predicted binding energy of your design. The target DDG is -40.0 or less.
SASA Score (max +0)
The solvent-accessible surface area that is lost upon binding. The target SASA is 1500 or more.
Shape Complementarity (max +0)
Measures how well your binder fits the contours of the target surface. The target Shape Complementarity is 0.60 or more.
Buried Unsats (max +500)
Penalizes 60 points for each polar atom that cannot make any H-bonds. Note that the frozen target includes 3 buried unsats that may be impossible to satisfy.
Residue Count (max +275)
Penalizes extra residues inserted beyond the starting 151, at a cost of 55 points per residue. Players may use up to 156 residues in total.
Core Existence (max +1000)
Ensures that at least 25 percent of residues are buried in the core of the monomer unit.
Ideal Loops (max +500)
Penalizes any loop region that does not match one of the Building Blocks in the Blueprint tool. Use "Auto Structures" to see which regions of your protein count as loops.
SS Design (max +500)
Penalizes all CYS residues. Penalizes GLY, ALA residues in sheets. Penalizes GLY, ALA, SER, THR in helices.