Foldit Lab Report #11: Deep Learning

Details of a new research paper that Foldit players contributed to! In it, scientists at the University of Washington and at Harvard developed a new, machine-learning based method for protein design. Watch our latest lab report for more.

NEWS
- How did Foldit help with the new deep learning paper?

PUZZLE UPDATES
- Coronavirus binders & anti-inflammatory design
- More symmetric design, and the problem of aggregation

DESIGN OF THE MONTH
- NinjaGreg made a sweet symmetric trimer!
See for yourself in the Design of the Month sandbox puzzle!

(Sat, 08/01/2020 - 13:20  |  2 comments)
spvincent's picture
User offline. Last seen 8 hours 41 min ago. Offline
Joined: 12/07/2007
Groups: Contenders
Tyrosine triangles

Are tyrosine triangles also problematic?

bkoep's picture
User offline. Last seen 4 hours 23 min ago. Offline
Joined: 11/15/2012
Groups: Foldit Staff
Yes

Good catch! This kind of geometry is problematic for all hydroxyl (-OH) groups, including the -OH at the tip of TYR.

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, RosettaCommons