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1867: Symmetric Trimer Design: Limited Interface
Status: Closed
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Evolvers
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| 1 | Bletchley Park 9 14 | Contenders | 21,221 | 100 | | 2 | georg137 29 150 | Contenders | 21,192 | 97 | | 3 | CharlieFortsCon... 51 1376 | Contenders | 21,103 | 94 | | 4 | BootsMcGraw 12 11 | Contenders | 21,010 | 91 | | 5 | Joanna_H 51 1376 | Gargleblasters | 20,931 | 87 | | 6 | Pazithi 37 42 | Gargleblasters | 20,918 | 84 | | 7 | Mike Lewis 51 1376 | Gargleblasters | 20,916 | 81 | | 8 | OWM3 51 1376 | Gargleblasters | 20,910 | 78 | | 9 | HuubR 23 53 | Gargleblasters | 20,910 | 76 | | 10 | Skippysk8s 47 56 | Gargleblasters | 20,909 | 73 | | 11 | mirp 51 1376 | Go Science | 20,891 | 70 | | 12 | Dhalion 26 300 | Go Science | 20,887 | 68 | | 13 | Czim 51 1376 | Go Science | 20,886 | 65 | | 14 | Bruno Kestemont 4 5 | Go Science | 20,875 | 63 | | 15 | ichwilldiesennamen 25 10 | Go Science | 20,874 | 60 | | 16 | Blipperman 51 76 | Gargleblasters | 20,846 | 58 | | 17 | Galaxie 1 2 | Anthropic Dreams | 20,810 | 56 | | 18 | lynnai 51 1376 | Anthropic Dreams | 20,787 | 54 | | 19 | phi16 10 43 | Anthropic Dreams | 20,774 | 52 | | 20 | alwen 51 1376 | Anthropic Dreams | 20,744 | 50 | | 21 | robgee 15 18 | Anthropic Dreams | 20,740 | 48 | | 22 | Anfinsen_slept_here 13 35 | Go Science | 20,713 | 46 | | 23 | Jpilkington 51 1376 | Gargleblasters | 20,704 | 44 | | 24 | alcor29 5 8 | Anthropic Dreams | 20,545 | 41 | | 25 | LociOiling 2 1 | Beta Folders | 20,526 | 39 | Need this puzzle? Log in to download.
Comments
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Buried Unsats (max +500)
Penalizes polar atoms that cannot make hydrogen bonds, -150 points per atom (not including symmetric copies).
Core Existence: Monomer (max +2000)
Ensures that at least 30 residues are buried in the core of the monomer unit.
Core Limit: Complex (max +500)
Checks that no more than 102 residues are buried in the symmetric complex, including the interface between monomer units.
SS Design (max +500)
Penalizes all CYS residues. Penalizes GLY, ALA residues in sheets. Penalizes GLY, ALA, SER, THR in helices.
Ideal Loops (max +500)
Penalizes any loop region that does not match one of the Building Blocks in the Blueprint tool. Use "Auto Structures" to see which regions of your protein count as loops.