puzzle picture
1867: Symmetric Trimer Design: Limited Interface
Status: Closed

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RankGroupScorePoints
1Contenders21,221100
2Gargleblasters20,97370
3Go Science20,89147
4Anthropic Dreams20,81030
5Beta Folders20,53819
6Void Crushers20,50511
7L'Alliance Francophone19,4937
8Marvin's bunch19,2894
9BOINC@Poland18,7762
10Hold My Beer16,6321
11Australia15,9981
12Russian team15,7551
13Italiani Al Lavoro11,4591
14Mojo Risin'01
15Team Canada01


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bkoep's picture
User offline. Last seen 19 hours 3 min ago. Offline
Joined: 11/15/2012
Groups: Foldit Staff
Objectives

Buried Unsats (max +500)
Penalizes polar atoms that cannot make hydrogen bonds, -150 points per atom (not including symmetric copies).

Core Existence: Monomer (max +2000)
Ensures that at least 30 residues are buried in the core of the monomer unit.

Core Limit: Complex (max +500)
Checks that no more than 102 residues are buried in the symmetric complex, including the interface between monomer units.

SS Design (max +500)
Penalizes all CYS residues. Penalizes GLY, ALA residues in sheets. Penalizes GLY, ALA, SER, THR in helices.

Ideal Loops (max +500)
Penalizes any loop region that does not match one of the Building Blocks in the Blueprint tool. Use "Auto Structures" to see which regions of your protein count as loops.

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, Boehringer Ingelheim, RosettaCommons