Thu, 07/16/2020 - 20:53
#2
Complex core: (no?) limits
The last sentence of the Description ("no limits on the Complex Core", "H-bond Networks") confuses me. It seems to contradict the first part of the description: "no H-Bond Network objective, but there is "Core Limit: Complex" objective".
Was the last sentence unintentionally copied from the previous Symmetry puzzles, or am I missing the point here?
Buried Unsats (max +500)
Penalizes polar atoms that cannot make hydrogen bonds, -150 points per atom (not including symmetric copies).
Core Existence: Monomer (max +2000)
Ensures that at least 20 residues are buried in the core of the monomer unit.
Core Limit: Complex (max +500)
Checks that no more than 72 residues are buried in the symmetric complex, including the interface between monomer units.
SS Design (max +500)
Penalizes all CYS residues. Penalizes GLY, ALA residues in sheets. Penalizes GLY, ALA, SER, THR in helices.
Ideal Loops (max +500)
Penalizes any loop region that does not match one of the Building Blocks in the Blueprint tool. Use "Auto Structures" to see which regions of your protein count as loops.