puzzle picture
1841: Coronavirus NSP6 Prediction
Status: Closed


Name: 1841: Coronavirus NSP6 Prediction
Status: Closed
Created: 05/21/2020
Points: 0
Expired: 05/28/2020 - 23:00
Difficulty: Intermediate
Description: Note: This puzzle was originally posted with an incorrect sequence. It was closed early and replaced by Puzzle 1841b.

Fold this coronavirus protein! This is a portion of a larger protein encoded in the viral genome of SARS-CoV-2. It is encoded in a region of the genome called NSP6, but the protein's structure and function are still unknown. If we knew how this protein folds, we might be able to figure out its exact function. The puzzle's starting structure shows SS predictions from PSIPRED, and hints which parts of the protein might fold into helices or sheets. Refold this protein to find high-scoring solutions, which will tell us how this protein is most likely to fold!


Top Groups

2Go Science9,9860
3L'Alliance Francophone9,2500
4Anthropic Dreams9,0050

Top Evolvers

1puxatudo 20 223 Go Science9,7840
2fisherlr777 40 699 Go Science9,7720

Top Soloists

1infjamc 34 57 Contenders10,4490
2NinjaGreg 29 11 Go Science9,9860
3johnmitch 113 20  9,6990
4ZeroLeak7 47 16 Go Science9,6400
5CAN1958 113 124  9,3920

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Joined: 03/05/2015
Groups: Gargleblasters
Not the right sequence

Not the right sequence

Susume's picture
User offline. Last seen 12 hours 4 min ago. Offline
Joined: 10/02/2011
Gave us 1835 again

The AA sequence in the game is the same one we had for 1835, an nsp2 domain. The sequence in the puzzle comments is for an nsp6 domain - probably what we were supposed to get.

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