puzzle picture
1800: Poly-Proline Helix Design: Round 9
Status: Closed

Summary

Name: 1800: Poly-Proline Helix Design: Round 9
Status: Closed
Created: 02/13/2020
Points: 100
Expired: 02/21/2020 - 23:00
Difficulty: Intermediate
Description: This is the ninth puzzle in the poly-proline helix design series! The starting structure is still a 90 residue protein with a 6 residue helix. All residues are mutable, and keeping all buried polars satisfied remains a key component of a good structure, as is a hydrophobic core and well defined secondary structures. We should be introducing a score filter very soon which will allow you to see what atoms are problematic. This should be a big help to Foldit players!
Categories: Design, Overall

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1Go Science11,790100
2Anthropic Dreams11,72273
3Contenders11,51552
4L'Alliance Francophone11,37936
5Beta Folders11,22724

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, Boehringer Ingelheim, RosettaCommons