puzzle picture
1779: Symmetric Tetramer Design: H-bond Networks
Status: Closed


1Anthropic Dreams23,612100
2Go Science23,50371
3Beta Folders23,43049
6L'Alliance Francophone22,84414
7Void Crushers22,6638
8Marvin's bunch22,5895
9Russian team21,2703
10Team Schleswig-Holstein20,9512
12Team New Zealand16,6801
15Italiani Al Lavoro10,9111
16Hun-Magyar Csapat01

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bkoep's picture
User offline. Last seen 3 days 11 hours ago. Offline
Joined: 11/15/2012
Groups: Foldit Staff

Core Existence: Monomer (max +2800)
Ensures that at least 28 residues are buried in the core of the monomer unit.

Core: Complex (max +0)
Awards no bonuses or penalties. Click Show to see which residues count as "Core" for the H-bond Network objective.

H-bond Network (max +2400)
Rewards networks that comprise at least two H-bonds involving core residues.
Between 1 and 12 H-bonds should cross the interface between symmetric units.
Networks must be at least 75% satisfied (i.e. 75% of all bondable atoms in a network must make a H-bond).

SS Design (max +500)
Penalizes all CYS residues. Penalizes GLY, ALA residues in sheets. Penalizes GLY, ALA in helices.

Ideal Loops (max +500)
Penalizes any loop region that does not match one of the Building Blocks in the Blueprint tool. Use "Auto Structures" to see which regions of your protein count as loops.

LociOiling's picture
User offline. Last seen 8 hours 8 min ago. Offline
Joined: 12/27/2012
Groups: Beta Folders
from vet chat...

A few comments about using the blueprint tool on symmetry puzzles.

[15:50] HI. Is blueprint acting up? Lately the inserts seem to resist pasting into the matrix.
[16:37]<@MikeCassidytoo> I didnt have trouble yesterday
[17:53] @alcor29: turn off Show Symmetric Chains
[18:01] Thanks spvincent.
[18:01] yw. (vakobo found that one)
[18:02] good catch

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, RosettaCommons