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1742: IL-7R Binder Redesign: Round 19
Status: Closed
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Soloists
1 | Bletchley Park 14 52 | Contenders | 11,245 | 100 | 2 | Enzyme 52 2 | Gargleblasters | 11,240 | 95 | 3 | johnmitch 89 12 | | 11,229 | 89 | 4 | ZeroLeak7 18 4 | Go Science | 11,217 | 84 | 5 | dcrwheeler 89 6 | | 11,209 | 79 | 6 | Phyx 64 37 | Go Science | 11,192 | 74 | 7 | phi16 13 17 | Anthropic Dreams | 11,181 | 69 | 8 | Galaxie 6 9 | Anthropic Dreams | 11,179 | 65 | 9 | Bruno Kestemont 2 7 | Go Science | 11,176 | 61 | 10 | fiendish_ghoul 89 11 | | 11,170 | 57 | 11 | retiredmichael 89 1596 | Beta Folders | 11,131 | 53 | 12 | LociOiling 9 5 | Beta Folders | 11,107 | 50 | 13 | Timo van&n... 89 475 | Void Crushers | 11,079 | 46 | 14 | Glen B 89 825 | | 11,072 | 43 | 15 | Vinara 89 49 | | 11,070 | 40 | 16 | silent gene 7 13 | Go Science | 11,069 | 37 | 17 | spvincent 36 15 | Contenders | 11,067 | 35 | 18 | Anfinsen_slept_here 28 38 | Go Science | 11,052 | 32 | 19 | vakobo 89 2571 | Russian team | 11,026 | 30 | 20 | jamiexq 89 183 | Anthropic Dreams | 10,981 | 28 | 21 | id566488 89 2571 | | 10,936 | 26 | 22 | jobo0502 89 28 | L'Alliance Francophone | 10,928 | 24 | 23 | Hellcat6 68 87 | Go Science | 10,916 | 22 | 24 | robgee 12 16 | Anthropic Dreams | 10,908 | 20 | 25 | Blipperman 23 35 | Gargleblasters | 10,906 | 19 | Need this puzzle? Log in to download.
Comments
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Residue IE Score (max +500)
Monitors that all PHE, TYR, and TRP residues are scoring well.
Core Existence (max +1000)
Ensures that at least 25% of residues are buried in the protein core.
SS Design (max +300)
Penalizes all CYS residues. Penalizes GLY, ALA, SER, THR in helices. Penalizes GLY, ALA in sheets.
Residue Count (max +100)
Penalizes extra residues inserted beyond 110, at a cost of 20 points per residue. Players may use up to 115 residues in total.