puzzle picture
1738b: IL-7R Binder Redesign: Round 17
Status: Closed

Groups

RankGroupScorePoints
1Gargleblasters11,858100
2Beta Folders11,83770
3Anthropic Dreams11,81847
4Go Science11,81130
5Contenders11,77119
6L'Alliance Francophone11,71811
7Hun-Magyar Csapat11,6487
8Russian team11,6254
9Marvin's bunch11,6172
10Void Crushers11,5921
11Italiani Al Lavoro11,0261
12Team New Zealand10,9131
13Trinity Biology10,2321
14MU Biochemisty I Fall 2019 Goode8,5961
1520198,3261


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bkoep's picture
User offline. Last seen 39 min 11 sec ago. Offline
Joined: 11/15/2012
Groups: None
Objectives

Residue IE Score (max +500)
Monitors that all PHE, TYR, and TRP residues are scoring well.

Core Existence (max +1000)
Ensures that at least 25% of residues are buried in the protein core.

SS Design (max +400)
Penalizes all CYS residues. Penalizes GLY, ALA, SER, THR in helices. Penalizes GLY, ALA in sheets.

Residue Count (max +100)
Penalizes extra residues inserted beyond 110, at a cost of 20 points per residue. Players may use up to 115 residues in total.

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, RosettaCommons