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1729: Symmetric Dimer Design: 60 Residues
Status: Closed
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Evolvers
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| 1 | jausmh 33 65 | Marvin's bunch | 17,686 | 100 | | 2 | fpc 41 22 | Marvin's bunch | 17,651 | 95 | | 3 | Blipperman 28 40 | Gargleblasters | 17,608 | 90 | | 4 | ManVsYard 93 1642 | Gargleblasters | 17,605 | 85 | | 5 | actiasluna 93 2641 | Gargleblasters | 17,603 | 80 | | 6 | Skippysk8s 20 25 | Gargleblasters | 17,539 | 76 | | 7 | Galaxie 5 9 | Anthropic Dreams | 17,526 | 68 | | 8 | mberna00 71 1401 | Anthropic Dreams | 17,506 | 64 | | 9 | robgee 12 15 | Anthropic Dreams | 17,487 | 60 | | 10 | lamoille 93 2641 | Anthropic Dreams | 17,486 | 56 | | 11 | phi16 13 18 | Anthropic Dreams | 17,481 | 53 | | 12 | alcor29 11 73 | Anthropic Dreams | 17,468 | 50 | | 13 | alwen 38 222 | Anthropic Dreams | 17,462 | 47 | | 14 | jamiexq 93 131 | Anthropic Dreams | 17,462 | 44 | | 15 | LociOiling 8 3 | Beta Folders | 17,438 | 41 | | 16 | dbuske 93 2641 | Beta Folders | 17,320 | 39 | | 17 | Bruno Kestemont 2 8 | Go Science | 17,107 | 36 | | 18 | Anfinsen_slept_here 40 49 | Go Science | 17,099 | 34 | | 19 | Hollinas 68 1139 | Go Science | 17,093 | 32 | | 20 | silent gene 6 11 | Go Science | 17,055 | 29 | | 21 | Willyanto 93 2641 | Go Science | 16,919 | 27 | | 22 | O Seki To 93 2641 | Hun-Magyar Csapat | 16,635 | 26 | | 23 | retiredmichael 93 1642 | Beta Folders | 11,287 | 24 | Need this puzzle? Log in to download.
Comments
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Core Existence: Monomer (max +1700)
Ensures that at least 17 residues are buried in the core of the monomer unit.
SS Design (max +500)
Penalizes all CYS residues. Penalizes GLY, ALA residues in sheets. Penalizes GLY, ALA, SER, THR in helices.
Ideal Loops (max +500)
Penalizes any loop region that does not match one of the Building Blocks in the Blueprint tool. Use "Auto Structures" to see which regions of your protein count as loops.
Secondary Structure (max +500)
No more than 50% of residues may form helices. Extra helices are penalized at 10 points per residue.