i'v got +250 instead of +200
Hmm, that shouldn't be possible... Can you share your solution with scientists? Could be a bug.
Quote
"This is the seventh puzzle in the IL-7R binder series"
Really !! Are you sure ??
Glad to see some close reading of the puzzle descriptions ;)
I've shared this solution. It is very unstable - any wiggle drops +250 bonus down to normal value
As noted by JSmith48 in global chat, segments 46-51 can move.
If you draw 3 bands from these segments to a point in space, and change the strength of each band to 10, wiggle will move the section a long way. The other snippets of IL-7R can't be moved this way.
When you disable or delete the bands, there is some tendency for 46-51 to migrate back closer to where it started. It never shows any red constraint lines, however, even with "show constraints" checked in view options.
That was an oversight on our part; segments 46-51 are supposed to be fixed in place! I don't expect this to have a huge effect on the puzzle results, but we'll have to take a close look at the solutions after the puzzle closes.
I checked the previous four rounds of this series. Segments 46-51 don't move in these puzzles.
lots of us found ourselves locked out due to server shut down. If you need a revisit let us know, though Fiendish has a stunning fold for this
Shared it with scientists. Segment 65 became valid
Residue IE Score (max +500)
Monitors that all PHE, TYR, and TRP residues are scoring well.
Core Existence (max +1000)
Ensures that at least 25% of residues are buried in the protein core.
SS Design (max +200)
Penalizes all CYS residues. Penalizes GLY, ALA, SER, THR in helices. Penalizes GLY, ALA in sheets.
Residue Count (max +100)
Penalizes extra residues inserted beyond 110, at a cost of 20 points per residue. Players may use up to 115 residues in total.