puzzle picture
Beginner Puzzle (<150): Symmetry Design
Status: Closed


Name: Beginner Puzzle (<150): Symmetry Design
Status: Closed
Created: 01/27/2014
Points: 100
Expired: 06/07/2018 - 23:00
Difficulty: Beginner
Description: This is a small symmetric trimer design puzzle. A symmetric protein relies not only on how well folded each part is, but also on how well they interface together. Your changes will be reflected in the symmetric unit. Make sure you have completed Intro Puzzle 5-2, and 7-1 through 7-4. For players with fewer than 150 global points.


If you are new to Foldit, here are detailed instructions to get you started:

If you want to fold proteins, know that there are many ways to play and this variety is the main value of Foldit :
- try all puzzles not only "Beginners" ones,
- fold first the ones you like the most,
- try it by yourself to understand what works and what doesn't,
- ask for tips in global chat when you think you don't understand something.

Make sure you have followed these tutorials:
- Lonely Sheets,
- Lock and Lower,
- Rebuild,
- Structure and Rebuild,
- Movin' Along,
- Control over Clashing,
- Intro to Design,
- Swappin' Sidechains,
- Mass Mutate,
- Insertion and Deletion

before starting this puzzle.

Categories: Beginner

Top Groups

1Hun-Magyar Csapat13,0750
4Go Science11,6950
5Richard Dawkins Foundation10,2180

Top Soloists

1Ribo-soma 46 1373 Hun-Magyar Csapat13,075100
2MarkinM 46 1373  12,46991
3khalan.ysatis 46 1373  12,40983
4Jesse Pinkman 46 1373  12,07475
5GaryForbis 46 1373 Contenders12,00568

Need this puzzle? Log in to download.  


Joined: 03/08/2012
Groups: None
Mutate-Button not giving usual results

Hi, as NON beginner I'm getting 11900 points, but it appears that the mutate-Button wan't give the usual results - in No. of hydrophobics. Manual mutation to hydrophobics is working, but gives less points.

Q: Something wrong in this puzzle settings?

bkoep's picture
User offline. Last seen 7 hours 19 min ago. Offline
Joined: 11/15/2012
Groups: Foldit Staff
Corrected in future puzzles

Thanks for the note WBarme1234! One of the recent updates changed how scoring works in Foldit, and the puzzles need to be tweaked accordingly. The Beginner puzzles slipped through the cracks, and that's why you're seeing this weird behavior. We may leave this puzzle as is, for the sake of convenience, but when it is recycled, the weird behavior should be corrected.

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, Boehringer Ingelheim, RosettaCommons