Puzzle 1465 "SCORING BUG"

Case number:699969-2004641
Topic:General
Opened by:ZeroLeak7
Status:Open
Type:Bug
Opened on:Friday, January 5, 2018 - 14:55
Last modified:Saturday, January 6, 2018 - 21:50

Hello,

We have a problem with puzzle 1465 a player https://fold.it/portal/user/317303 from my Group has found a glitch or bug.

He had a score of 10181 and it popped up to 10913 as he pulled an wiggled the protein.

(Fri, 01/05/2018 - 14:55  |  4 comments)


LociOiling's picture
User offline. Last seen 2 hours 41 min ago. Offline
Joined: 12/27/2012
Groups: Beta Folders

I see that Maerlyn138 has taken a big lead on 1465. The high score was 10,475 the last time we revisited this protein, so a score of 10,913 indicates there may indeed be a problem.

I'd suggest sharing the the high-scoring solution, then having someone else in the group try to open it. You may find it opens with a much lower score, while still requiring the high score plus two points to evo.

Alternately, it's just possible that you actually have a much better solution. The native for this one is seen in PDB 1RKI. It's a protein from Pyrobaculum aerophilum, which grows best around the boiling point for water. Maybe growing this protein in good old E. coli isn't quite the same.

1RKI does look a little sketchy. It's a dimer, with two copies of the protein. To me, it's hard to see what's holding the two copies together.

We're only working with one copy, but even so, it has issues. There are two groups of sheets. The outer group has three sheets. A long 8-segment loop section crosses over the middle sheet on the outside of the protein. This seems a little unusual.

So here's hoping we have a better solution. We don't really need another scoring bug.

Hanto's picture
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Joined: 05/10/2008
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Maerlyn, do NOT stop. keep going!!!!!

Hanto's picture
User offline. Last seen 20 hours 49 min ago. Offline
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I should ask tho, were you using TRACKs when this apparent bug occurred on the client in question?

Hanto's picture
User offline. Last seen 20 hours 49 min ago. Offline
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Or were you using multiple foldit executables inside a single folder/directory?

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