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1435: Extra Large Monomer Design
Status: Closed
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Evolvers
1 | Galaxie 1 2 | Anthropic Dreams | 11,064 | 100 | 2 | phi16 9 30 | Anthropic Dreams | 11,057 | 97 | 3 | lamoille 46 1603 | Anthropic Dreams | 11,057 | 93 | 4 | actiasluna 46 1603 | Gargleblasters | 11,055 | 90 | 5 | alcor29 5 9 | Anthropic Dreams | 11,052 | 86 | 6 | gdnskye 46 1603 | Anthropic Dreams | 11,051 | 83 | 7 | Skippysk8s 34 28 | Gargleblasters | 11,046 | 80 | 8 | Enzyme 46 1603 | Gargleblasters | 11,046 | 76 | 9 | Blipperman 26 31 | Gargleblasters | 11,042 | 73 | 10 | LociOiling 2 1 | Beta Folders | 10,827 | 71 | 11 | reefyrob 46 374 | Beta Folders | 10,824 | 68 | 12 | smilingone 46 194 | Beta Folders | 10,822 | 65 | 13 | Bruno Kestemont 3 3 | Go Science | 10,805 | 62 | 14 | toshiue 46 949 | Go Science | 10,804 | 60 | 15 | andrewxc 46 365 | Gargleblasters | 10,785 | 57 | 16 | SaraL 46 1603 | Gargleblasters | 10,757 | 55 | 17 | georg137 18 34 | Contenders | 10,686 | 53 | 18 | Hollinas 46 1603 | Go Science | 10,662 | 50 | 19 | tamanrasset 46 1603 | Marvin's bunch | 10,530 | 48 | 20 | harvardman 46 554 | Anthropic Dreams | 9,134 | 46 | 21 | alwen 46 554 | Anthropic Dreams | 9,111 | 44 | Need this puzzle? Log in to download.
Comments
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Residue IE Score: Monitors that all PHE, TYR, and TRP residues are scoring well.
Core Existence: Ensures that at least 35% of the residues are buried in the core of your design.
Secondary Structure: Checks that no more than 50% of residues are in helices; penalties are incurred if more than 50% of residues form helices.
Secondary Structure Design: Penalizes all CYS residues. Penalizes GLY, ALA residues in sheets; penalizes GLY, ALA, SER, THR in helices.
Residue Count: Penalizes extra residues inserted beyond the starting 95. Players may use up to 120 residues in total.
Ideal Loops: Penalizes loops that do not conform to preferred ABEGO patterns. Use Auto Structures to see which residues count as "loops."