puzzle picture
1424: Extra Large Monomer Design
Status: Closed

Summary

Name: 1424: Extra Large Monomer Design
Status: Closed
Created: 09/01/2017
Points: 100
Expired: 09/08/2017 - 23:00
Difficulty: Intermediate
Description: This puzzle challenges players to design a single-chain protein with 95-120 residues. We've adjusted the scoring function here so that alanine residues are more tolerable in loops (they are still restricted in helices and sheets!). The starting structure has 95 residues, but more can be added at a cost of 23 points per residue. See the puzzle comments for filter details. The Baker Lab will run folding predictions on your solutions for this puzzle, and those that perform well will be synthesized in the lab. Remember, you can use the Upload for Scientists button for up to 5 designs that you want us to look at, even if they are not the best-scoring solutions!
Categories: Design, Overall

Top Groups

RankGroupScorePoints
1Gargleblasters11,040100
2Beta Folders10,99070
3Anthropic Dreams10,97147
4Contenders10,82730
5Go Science10,78319

Top Evolvers

Top Soloists

RankPlayerGroupScorePoints
1Enzyme 17 1 Gargleblasters11,036100
2markm457 85 16 Anthropic Dreams10,97197
3LociOiling 2 2 Beta Folders10,97193
4eusair 85 12  10,86689
5crpainter 52 8 Contenders10,82786


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Comments

Joined: 09/11/2017
Groups: None
BIO121

I like the BIO lab

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Microsoft, Adobe, RosettaCommons