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1342: 65 Residue Monomer Design: Blueprint
Status: Closed
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Evolvers
1 | LociOiling 8 3 | Beta Folders | 10,207 | 100 | 2 | reefyrob 91 2622 | Beta Folders | 10,207 | 98 | 3 | smilingone 91 2622 | Beta Folders | 10,207 | 95 | 4 | Galaxie 6 9 | Anthropic Dreams | 10,204 | 93 | 5 | retiredmichael 91 1639 | Beta Folders | 10,203 | 90 | 6 | jfryk 91 2622 | Anthropic Dreams | 10,199 | 88 | 7 | lamoille 91 2622 | Anthropic Dreams | 10,196 | 86 | 8 | JayD7217 91 2622 | Go Science | 10,177 | 83 | 9 | Bruno Kestemont 2 8 | Go Science | 10,175 | 81 | 10 | jamiexq 91 129 | Anthropic Dreams | 10,138 | 77 | 11 | Bletchley Park 11 53 | Contenders | 10,102 | 74 | 12 | georg137 42 132 | Contenders | 10,070 | 72 | 13 | mimi 91 2622 | Contenders | 10,069 | 70 | 14 | Cyberkashi 91 2622 | Contenders | 10,067 | 68 | 15 | gitwut 91 2622 | Contenders | 10,063 | 66 | 16 | Hollinas 68 1136 | Go Science | 9,833 | 65 | 17 | dbuske 91 2622 | Beta Folders | 9,792 | 63 | 18 | NinjaGreg 24 19 | Go Science | 9,764 | 61 | 19 | alwen 38 222 | Anthropic Dreams | 9,718 | 59 | 20 | alcor29 10 73 | Anthropic Dreams | 9,636 | 57 | 21 | phi16 14 18 | Anthropic Dreams | 9,606 | 56 | 22 | harvardman 91 2622 | Anthropic Dreams | 9,600 | 54 | 23 | gu14016 91 2622 | GUGITBIOTECH | 9,001 | 53 | 24 | heyubob 91 184 | Gargleblasters | 8,830 | 51 | 25 | SaraL 91 679 | Gargleblasters | 8,761 | 49 | Need this puzzle? Log in to download.
Comments
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Residue IE Score: Monitors that all PHE, TYR, and TRP residues are scoring well.
Core Existence: Ensures that at least 30% of the residues are buried in the core of your design.
Secondary Structure: Checks that no more than 50% of residues are in helices; penalties are incurred if more than 50% of residues form helices.
Secondary Structure Design: Penalizes all CYS residues. Penalizes GLY and ALA residues in helices and sheets.
Residue Count: Penalizes extra residues inserted beyond the 65 residue limit. Players may insert up to 10 extra residues.
Ideal Loops: Penalizes loops that do not conform to preferred ABEGO patterns. Use Auto Structures to see which residues count as "loops."