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1342: 65 Residue Monomer Design: Blueprint
Status: Closed
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Groups
1 | Beta Folders | 10,207 | 100 | 2 | Anthropic Dreams | 10,204 | 81 | 3 | Go Science | 10,178 | 64 | 4 | Contenders | 10,102 | 50 | 5 | Void Crushers | 10,062 | 39 | 6 | L'Alliance Francophone | 9,992 | 30 | 7 | Gargleblasters | 9,959 | 23 | 8 | Another Hour Another Point | 9,868 | 17 | 9 | Italiani Al Lavoro | 9,532 | 12 | 10 | Androids | 9,449 | 9 | 11 | GUGITBIOTECH | 9,030 | 6 | 12 | FoldIt@Netherlands | 8,924 | 4 | 13 | Team South Africa | 8,520 | 3 | 14 | xkcd | 8,079 | 2 | 15 | E?????! Heureka! | 7,549 | 1 | 16 | Kotocycle | 5,364 | 1 | 17 | Natural Abilities | 5,346 | 1 | 18 | LEC Metabolites | 3,837 | 1 | 19 | BioChem22017 | 3,773 | 1 | 20 | DSN @ Home | 3,461 | 1 | 21 | Penn State Biomolecular Engineers | 0 | 1 | 22 | Richard Dawkins Foundation | 0 | 1 | 23 | BMB401_SP17 | 0 | 1 | 24 | HCC BIOL121 S2017 | 0 | 1 | Need this puzzle? Log in to download.
Comments
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Residue IE Score: Monitors that all PHE, TYR, and TRP residues are scoring well.
Core Existence: Ensures that at least 30% of the residues are buried in the core of your design.
Secondary Structure: Checks that no more than 50% of residues are in helices; penalties are incurred if more than 50% of residues form helices.
Secondary Structure Design: Penalizes all CYS residues. Penalizes GLY and ALA residues in helices and sheets.
Residue Count: Penalizes extra residues inserted beyond the 65 residue limit. Players may insert up to 10 extra residues.
Ideal Loops: Penalizes loops that do not conform to preferred ABEGO patterns. Use Auto Structures to see which residues count as "loops."