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1336: 70 Residue Monomer Design: Blueprint
Status: Closed


Name: 1336: 70 Residue Monomer Design: Blueprint
Status: Closed
Created: 02/02/2017
Points: 100
Expired: 02/09/2017 - 23:00
Difficulty: Intermediate
Description: This puzzle omits the Ideal Loop Filter; we're leaving it up to players to find their own high-scoring loops! The Blueprint panel is still available, which can be accessed from the Actions menu (or the Main menu in Selection Interface). Like other recent puzzles, the Rebuild action has been disabled here; in its place we encourage players to use Remix instead. See the puzzle comments for filter details. The Baker Lab will run folding predictions on your solutions for this puzzle, and those that perform well will be synthesized in the lab. Remember, you can use the Upload for Scientists button for up to 5 designs that you want us to look at, even if they are not the best-scoring solutions!
Categories: Design, Overall

Top Groups

1Anthropic Dreams10,378100
2Beta Folders10,33971
3Go Science10,30749

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bkoep's picture
User offline. Last seen 2 hours 41 min ago. Offline
Joined: 11/15/2012
Groups: None

Residue IE Score: Monitors that all PHE, TYR, and TRP residues are scoring well.

Core Existence: Ensures that at least 30% of the residues are buried in the core of your design.

Secondary Structure: Checks that no more than 50% of residues are in helices; penalties are incurred if more than 50% of residues form helices.

Secondary Structure Design: Penalizes all CYS residues. Penalizes GLY, ALA, and PRO residues in helices and sheets.

Residue Count: Penalizes extra residues inserted beyond the 70 residue limit. Players may insert up to 10 extra residues.

bertro's picture
User offline. Last seen 5 hours 21 min ago. Offline
Joined: 05/02/2011
Groups: Beta Folders
This puzzle does not show on

This puzzle does not show on the puzzle list. And I cannot get it using the above link ...

bkoep's picture
User offline. Last seen 2 hours 41 min ago. Offline
Joined: 11/15/2012
Groups: None
Try now

Hmm, it looks like something on the server failed to update—I just updated it manually. Can you see the puzzle in the puzzle menu now?

Joined: 05/18/2012
Groups: Contenders
No client side group/soloist score either

I'm not seeing any client side group/soloist scores (24 hours after release).

Puzzle 1337 is also not displayed in my client puzzle listings.

Joined: 09/24/2012
Groups: Go Science
No scoreboard on client

Only on puzzle page

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, RosettaCommons