Puzzle 1315, segment 129 (?)

Case number:671071-2003192
Topic:Game: Other
Opened by:gitwut
Opened on:Thursday, December 8, 2016 - 18:50
Last modified:Friday, December 9, 2016 - 05:28

Why is there a segment (or ghost of segment) 129 floating around in puzzle 1315? Could it be causing part of the problem people are having? See attached image.

(Thu, 12/08/2016 - 18:50  |  4 comments)

gitwut's picture
User offline. Last seen 3 years 2 weeks ago. Offline
Joined: 05/18/2012
Groups: Contenders

I choose the image file, attached and previewed it in the above post. When I saved the post it didn't show up. What gives?

Grr. Image is 200MB.


Joined: 12/27/2012
Groups: Beta Folders

Looks like you found the copper ion that's supposed to be located in the density. It's pretty well hidden, I was looking for it, but not seeing it. I finally had to turn off the density and switch to a light background to see it. Segment 129 has secondary structure type "M" (for "molecule"), making it a normal ligand. Many recipes will detect this type of ligand, and avoid working on it.

The puzzle comments say:

This structure also contains a copper ion, which has been already been placed in the density for you. Three residues are known to interact with this copper ion: HIS 46, CYS 112, and HIS 117.

So it might be possible to see the two histidines near the ion.

bkoep's picture
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Joined: 11/15/2012
Groups: Foldit Staff

That's correct. Segment 129 is the copper ion, which is supposed to be placed within the density cloud. Most, if not all, of the crashes in puzzle 1315 result from a problem with this copper atom. I'm not sure why you're seeing the copper ion at a position distant from the density cloud. gitwut, did you load a saved solution or restart the puzzle before taking this screenshot?

gitwut's picture
User offline. Last seen 3 years 2 weeks ago. Offline
Joined: 05/18/2012
Groups: Contenders


No restarts or saved loads. I cut the SS up, placed them, used shake, wiggle and the tool to center it within the density cloud. It was then that I noticed segment 129 in the background. The script Loop explorer 3.01 detects segment 129 and wouldn't run correctly unless I specified segment ranges that excluded it (by default, it selects segment 1 through 129).


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