bkoep's picture
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Joined: 11/15/2012
Groups: Foldit Staff

Residue IE Score: Monitors that all PHE, TYR, and TRP residues are scoring well.

Core Existence: Ensures that at least 30% of the residues are buried in the core of your design.

Secondary Structure: Checks that no more than 50% of residues are in helices; penalties are incurred if more than 50% of residues form helices.

Secondary Structure Design: Penalizes all CYS residues. Penalizes GLY, ALA, and PRO residues in helices and sheets.

Residue Count: Penalizes extra residues inserted beyond the 85 residue limit. Players may insert up to 10 extra residues.

Ideal Loops: Penalizes loops that do not conform to preferred ABEGO patterns. Use Auto Structures to see which residues count as "loops."

Joined: 09/24/2012
Groups: Go Science

I can go to 95 residues

Joined: 05/19/2009
Groups: Contenders
95 with a penalty of 10000

Bruno, yes you can but the penalty for adding residues over 85 should quickly deter you from doing so. I noticed a 10000 point penalty for 95 residues.

Joined: 09/24/2012
Groups: Go Science

indeed, I didn't notice while I was in huge negative points

alwen's picture
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Joined: 10/03/2011
This is the slowest puzzle

This is the slowest puzzle I've worked on recently. It takes my PC as long as 10 minutes to grind through 3 iterations of wiggle. The fact that I'm on the scoreboard at all is only due to my stubbornness.

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, Boehringer Ingelheim, RosettaCommons