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1293b: Dysferlin C2B Domain: Predicted Contacts
Status: Closed


Name: 1293b: Dysferlin C2B Domain: Predicted Contacts
Status: Closed
Created: 10/07/2016
Points: 100
Expired: 10/14/2016 - 23:00
Difficulty: Intermediate
Description: Note: This puzzle replaces Puzzle 1293, which lacked a Contact Bonus filter. Players may load in solutions from Puzzle 1293.

This is a followup to Puzzle 1291, now with predicted contacts! This domain of the human dysferlin protein; see the blog for more info. Our collaborators at the Jain Foundation would like to model the structure of dysferlin to better understand its function, and have asked Foldit players to help! The structure of this protein domain is still unknown—fold up the extended chain to find a stable model and increase your score! Players may load in solutions from Puzzle 1291.

Categories: Overall, Predicted Contacts, Prediction

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Joined: 06/06/2013
Groups: Gargleblasters
contact map accuracy

can we assume this is mostly but not 100% correct? Thanks

bkoep's picture
User offline. Last seen 1 hour 27 min ago. Offline
Joined: 11/15/2012
Groups: Foldit Staff
High confidence

Yes, there is a lot of data to support these contact predictions. Most of the contacts are high confidence (bright green).

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, Boehringer Ingelheim, RosettaCommons