Foldit vs. UMich Electron Density Challenge
It is rally time! On Thursday, 22 October, we're releasing a special puzzle challenge for the Foldit community based on a structure of a protein recently solved by crystallographers in the Bardwell Lab at the University of Michigan.
We learned that before the team publishes the structure, they are challenging a class of undergraduate biochemistry students to build a model into this unrefined density map. Knowing our community would enjoy a challenge, the lab also has invited Foldit players to participate!
Here's what you need to know going in:
* The full sequence of the protein will be available; however, note that some parts of the protein are disordered and will not occupy any electron density.
* This puzzle is big, at 199 residues.
We have four weeks to develop a protein model that fits this density (the puzzle will close at 1pm ET/1700 UTC 19 November). Can Foldit players outperform the University of Michigan students—or even the crystallographers themselves?
Edit: The puzzle is LIVE!(Tue, 10/20/2015 - 16:24 | 8 comments)