The rundown on coronavirus

You don't have to be a scientist to do science! Download and play Foldit and you can help researchers discover new antiviral drugs that might stop coronavirus! The most promising solutions will be manufactured and tested at the University of Washington Institute for Protein Design in Seattle.

Foldit is run by academic research scientists. It is free to play and not-for-profit. To get started, download Foldit and create a username!

We recommend that new players start with the Foldit Intro Puzzles.
After some practice, move on to the Science Puzzles and try out the Beginner: Coronavirus puzzle.
We also have an advanced puzzle NEW advanced puzzle where you can try to design an antiviral protein from scratch!

To meet other players, check out the Foldit Discord channels.

Note: Foldit is an interactive computer game and not a distributed computing project. If you would like to donate idle CPU cycles to science, please check out the Rosetta@Home project on BOINC.

(Wed, 03/04/2020 - 05:46  |  9 comments)

A Reminder of the Community Rules

Hello all! Hope you are enjoying this fine Tuesday. I wanted to take a brief moment to remind everyone about the Foldit Community Rules. As part of the community, everyone is expected to adhere to these rules at all times, so it is important all are aware of what is expected. Here are the highlights:

  • Keep the conversation PG-rated, since there is a wide range of ages in the community. Anything deemed offensive or obscene will not be tolerated.
(Tue, 06/20/2017 - 22:30  |  1 comment)

Foldit Black Lives Matter Statement

Dear Foldit Players,

We had previously shared a statement in support of Black Lives Matter from the Rosetta Commons, of which Foldit is a part of. You can find that statement here. However, we have come to recognize that we have a separate Foldit community and acknowledge that it is crucial that we make our own statement:

(Thu, 08/06/2020 - 20:11  |  0 comments)

Developer Preview Release Soon

Hey everyone,

We're about to release an update to the developer preview with the following fixes:

Filters:
* Added a prototype objective for binder metrics.

Bug Fixes:
* Fixed an issue with 'Wiggle Lock' in some symmetric puzzles.
* Reduced some logfile spam.

(Thu, 08/06/2020 - 18:56  |  1 comment)

New Release!

Hey all,

We've just released an update with the following fix:

Bug Fixes:
* Fixed a crash related to enabling/disabling filters (https://fold.it/portal/node/2009855)

Thanks to our devprev players for testing this release! We have a few more bug fixes that should be coming to devprev shortly, so keep an eye out.

(Tue, 08/04/2020 - 18:55  |  0 comments)

Foldit Lab Report #11: Deep Learning

Details of a new research paper that Foldit players contributed to! In it, scientists at the University of Washington and at Harvard developed a new, machine-learning based method for protein design. Watch our latest lab report for more.

NEWS
- How did Foldit help with the new deep learning paper?

PUZZLE UPDATES
- Coronavirus binders & anti-inflammatory design
- More symmetric design, and the problem of aggregation

DESIGN OF THE MONTH
- NinjaGreg made a sweet symmetric trimer!
See for yourself in the Design of the Month sandbox puzzle!

(Sat, 08/01/2020 - 13:20  |  4 comments)

Try Foldit Education Mode!

Today we are releasing a separate app specifically for using Foldit for education, called Education Mode. Check out the blog for more details, and the new Educators page here if you want to download it.

(Sat, 08/01/2020 - 12:53  |  0 comments)

New blog post walk-through of research paper

See the blog for a walk-through of new research about energy landscape optimization!

Researchers used the work of Foldit players to help develop a new method for protein design. Due to their contributions, Foldit players will be listed as authors on the paper. The new blog post reviews the main points of the paper, but you can read a full pre-print here.

(Fri, 07/31/2020 - 21:39  |  0 comments)

Newsletter July 24: A Good Week for Go Science

Hey Folders! Missed the latest newsletter? Check it out on our blog here. Don't forget to sign up for the mailing list to receive weekly updates about Foldit!

(Wed, 07/29/2020 - 18:55  |  0 comments)

Foldit Newsletter July 17: Bonjour Encore Triple Hélice

Hey folders! Missed the latest newsletter? Check it out on our blog here. Don't forget to sign up for the mailing list here to receive weekly updates about Foldit!

(Fri, 07/24/2020 - 03:49  |  0 comments)
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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, RosettaCommons