The rundown on coronavirus

You don't have to be a scientist to do science! Download and play Foldit and you can help researchers discover new antiviral drugs that might stop coronavirus! The most promising solutions will be manufactured and tested at the University of Washington Institute for Protein Design in Seattle.

Foldit is run by academic research scientists. It is free to play and not-for-profit. To get started, download Foldit and create a username!

We recommend that new players start with the Foldit Intro Puzzles.
After some practice, move on to the Science Puzzles and try out the Beginner: Coronavirus puzzle.
We also have an advanced puzzle NEW advanced puzzle where you can try to design an antiviral protein from scratch!

To meet other players, check out the Foldit Discord channels.

Note: Foldit is an interactive computer game and not a distributed computing project. If you would like to donate idle CPU cycles to science, please check out the Rosetta@Home project on BOINC.

(Wed, 03/04/2020 - 05:46  |  9 comments)

A Reminder of the Community Rules

Hello all! Hope you are enjoying this fine Tuesday. I wanted to take a brief moment to remind everyone about the Foldit Community Rules. As part of the community, everyone is expected to adhere to these rules at all times, so it is important all are aware of what is expected. Here are the highlights:

  • Keep the conversation PG-rated, since there is a wide range of ages in the community. Anything deemed offensive or obscene will not be tolerated.
(Tue, 06/20/2017 - 22:30  |  1 comment)

New Release!

Hey everyone,

We've just released an update with some bug fixes and an exciting new feature:

New Feature: Metrics

Metrics are computationally expensive objectives. Since metrics take much longer to compute, we are handling them differently from normal objectives.

(Mon, 10/19/2020 - 23:08  |  0 comments)

Office Hour 10/17/20

Hey everyone! Bkoep will be having an Office Hour in #vet this Saturday, 10/17 at 10 AM Pacific time (17:00 GMT) Time Zone Converter. We noticed that there were a lot of questions regarding the Aflatoxin challenge and the Two-sided Interface design puzzle so please feel free to come with questions regarding those but please feel free to bring questions regarding other topics as well. Hope to see y'all there!

(Fri, 10/16/2020 - 00:28  |  0 comments)

Aflatoxin Challenge update

See the Foldit blog for the latest news and lab results for our Aflatoxin Challenge. The latest puzzle in the Aflatoxin Challenge is online now!

(Fri, 10/09/2020 - 18:09  |  0 comments)

Lab Report #13: Design better proteins with Metrics!

Can you believe there's already been a full year of Lab Reports? We have enjoyed making these video updates and look forward to sharing even more footage with you in the coming year. Watch our latest lab report on YouTube now.

- Foldit Metrics are now in devprev

- Binder design preparing for new Metrics

(Thu, 10/01/2020 - 09:49  |  0 comments)

Blog post on new Foldit Metrics

The latest devprev update includes a new Metrics feature! Metrics are slow to compute, and bring new challenges to Foldit. See the blog for more.

(Thu, 10/01/2020 - 09:49  |  0 comments)

Newsletter September 25: Raspberry Remix

Hey everyone! Be sure to view our latest newsletter!
Also, don't forget to sign up for the mailing list here to receive weekly updates about Foldit!

(Wed, 09/30/2020 - 03:47  |  0 comments)

Developer Preview Release Soon

Hey everyone,

We're about to release an update to the developer preview with some fixes and an exciting new feature:

New Feature: Metrics

Metrics are computationally expensive filters. Since metrics take much longer to compute, we are handling them differently from normal filters.

(Mon, 09/28/2020 - 19:09  |  7 comments)

New Release!

Hey everyone,

We're releasing a new update with the following fixes and changes:

BUNS Filter:
* Only sidechains with BUNS will be automatically shown when the filter is enabled.
* Some symmetric puzzles may now penalize BUNS across every asymmetric unit.
* When enabled, the filter will show every bondable atom without enabling any HBonds. This is new behavior for the 'show bondable atoms' view option as well, as clicking it will show all bondable atoms regardless of what particular HBond types are visible.

(Wed, 09/23/2020 - 20:13  |  0 comments)
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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, RosettaCommons