The rundown on coronavirus

You don't have to be a scientist to do science! Download and play Foldit and you can help researchers discover new antiviral drugs that might stop coronavirus! The most promising solutions will be manufactured and tested at the University of Washington Institute for Protein Design in Seattle.

Foldit is run by academic research scientists. It is free to play and not-for-profit. To get started, download Foldit and create a username!

We recommend that new players start with the Foldit Intro Puzzles.
After some practice, move on to the Science Puzzles and try out the Beginner: Coronavirus puzzle.
We also have an advanced puzzle NEW advanced puzzle where you can try to design an antiviral protein from scratch!

To meet other players, check out the Foldit Discord channels.

Note: Foldit is an interactive computer game and not a distributed computing project. If you would like to donate idle CPU cycles to science, please check out the Rosetta@Home project on BOINC.

(Wed, 03/04/2020 - 05:46  |  10 comments)

A Reminder of the Community Rules

Hello all! Hope you are enjoying this fine Tuesday. I wanted to take a brief moment to remind everyone about the Foldit Community Rules. As part of the community, everyone is expected to adhere to these rules at all times, so it is important all are aware of what is expected. Here are the highlights:

  • Keep the conversation PG-rated, since there is a wide range of ages in the community. Anything deemed offensive or obscene will not be tolerated.
(Tue, 06/20/2017 - 22:30  |  1 comment)

Office hour 9/17/21

Hey folks! We're going to be doing an Office Hour this Friday, 9/17 at 3 PM ET (Time Zone Converter). It will be led by beta_helix this time around. Come join us to chat about Electron Density--this is also an awesome opportunity to meet new Foldit Developer apetrides and discuss new ED tools (such as the new Select Cloud feature in Devprev).

(Thu, 09/16/2021 - 20:04  |  0 comments)

Developer Preview Release Soon

Hey everyone,

We're about to push an update to the developer preview with some fixes and changes:

General:
* The Deepmind Alphafold panel has been redesigned!
* You can now select the residues that fall within the visible sphere from the electron density panel.

Additionally, we have changed some things under the hood that shouldn't have an effect on the player experience, but let us know if you see anything odd.

(Tue, 09/14/2021 - 23:17  |  3 comments)

New Release - Foldit Education Mode!

Hey all,

We've just released an exciting new feature: Foldit Education Mode! This feature tunes the Foldit client to be more in line with how educators have wanted to use Foldit in the classroom over the years.

You may notice a prompt when you start up the new client for the first time asking if you want to use education mode - just leave this unchecked if you want regular foldit!

The full list of changes below:

General:
* Added a new Educational mode
* Added a quick question on your first login to allow toggling Education options

(Tue, 09/14/2021 - 23:11  |  0 comments)

Lab Report #24: Reviewing Your AlphaFold Designs

A first look at new Foldit designs enabled by AlphaFold!

NEWS
- Recap of AlphaFold

PUZZLE UPDATES
- Protein binder design for IL-2R and TGF-beta
- Ligand binder design cortisol
- Symmetric design puzzles

DESIGN OF THE MONTH

(Wed, 09/01/2021 - 13:47  |  1 comment)

Developer Preview Release Soon

Hey all,

We are about to release an update to the developer preview that moves our separate Education Mode client into the main game. This will make it easier for educators using Foldit to find and install the education mode.

You may notice a prompt when you start up the new client for the first time asking if you want to use education mode - just leave this unchecked if you want regular foldit!

The full list of changes below:

General:
* Added a new Educational mode

(Wed, 09/01/2021 - 13:45  |  1 comment)

New Release!

Hey all,

We've just released an update with some quick fixes:

Bug Fixes:
* Fixed certain situations where inserting/deleting residues could causing crashes with Alphafold results.
* The blueprint panel should no longer update while not visible.

Thank you to our devprev testers!

(Wed, 08/11/2021 - 22:05  |  0 comments)

Developer Preview Release Soon

Hey all,

We're about to release an update to the develop preview with some quick fixes:

Bug Fixes:
* Fixed certain situations where inserting/deleting residues could causing crashes with Alphafold results.
* The blueprint panel should no longer update while not visible.

(Tue, 08/10/2021 - 00:10  |  0 comments)

Office Hour 8/8/21

Hey everyone! We will be having an Office Hour led by Bkoep on Sunday, August 8th at 10 AM PT (Time Zone Converter).

(Sat, 08/07/2021 - 16:51  |  0 comments)
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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, Boehringer Ingelheim, RosettaCommons