Foldit Lab Report #10: Lab Results

Experimental results for 100 of your best anti-inflammatory binder designs — and the new Reaction Design tool for creating small molecule drugs. Watch our latest lab report for more.

- 100 anti-inflammatory designs have been tested
- Software update: Revamped intro and NEW Reaction Design Tool

Read more about the lab results on the blog

- Drug design for the Y1 receptor
- Coronavirus: binder design
- Coronavirus: anti-inflammatory design
- Symmetric design

- spvincent & Bletchley Park team up on trimer design!

(Wed, 07/01/2020 - 06:10  |  2 comments)

Experiment results for anti-inflammatory designs

The first experimental results are back for Foldit coronavirus anti-inflammatory designs! These experiments tested whether Foldit player designs could bind the the IL6R target. Check out the Foldit blog for more!

(Tue, 06/30/2020 - 23:48  |  0 comments)

Hotfix incoming

Hey everyone,

We're pushing out a hotfix today to address some of the issues that players have been having with the client. This will go out to devprev immediately, and main should follow soon after. Thank you for all the bug reports!

Bug Fixes:
* Fixed an issue with the crash reporter not clearing out old crash reports on Windows.
* Fixed a crash on Reaction Design puzzles.
* Fixed a crash due to OpenGL errors. Errors may still occur, but will be output to the logfile instead of crashing.
* Reduced logfile spam.

(Thu, 06/25/2020 - 21:44  |  1 comment)

New Release!

Hey everyone,

We're pushing out an update with the following fixes and features:

* Renamed the tutorial progression to "Campaign".
* The tutorial progression now follows a branching system instead of a straight linear progression.
* Added optional Science help bubbles to the tutorial text bubbles.
* Updated UI and text bubble colors to differentiate between various types of hint bubbles.

* A new feature has been added which will log messages which could be translated but aren't currently present in the active language pack to the file "untranslated_messages..log" in the working directory. Add the line "log_untranslated" : "1" to your options.txt file to enable.

Bug Fixes:
* Various crash fixes.

An especially big thanks to our devprev users for helping test a particularly rocky release! Sorry about that!

(Wed, 06/17/2020 - 19:49  |  8 comments)

Foldit Lab Report #9: Stay home, play games

A slew of new coronavirus puzzles and a software update that should improve all of your designs. Watch our latest lab report for more.

- 100 anti-inflammatory designs have been selected for lab testing
- A new software update will help beat back BUNS

- Coronavirus: structure prediction
- Coronavirus: inflammatory
- Coronavirus: binder design

- Migi's impressive backbone H-bonds

- DNA synthesis has been hampering our laboratory testing – but we have a work-around!

(Mon, 06/01/2020 - 15:26  |  4 comments)
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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, RosettaCommons