Excellent foldit model from CASP8!
One of the first scientific publications to showcase a Foldit model turns out to be an assessor's paper in the last CASP trials! Rhiju Das who was coordinating Foldit efforts in CASP8 noticed that the paper ("Assessment of the protein-structure refinement category in CASP8") highlights a Foldit model. Fig. 6 in this paper illustrates how a protein's 3D model submitted in CASP8 could help solve the "crystallographic phase problem" for this protein's experimental data, an important bottleneck in structural biology. The depicted model was made in the very early days of Foldit (summer of 2008) by Pletsch as part of the Another Hour Another Point team. The Foldit toolset has expanded a lot since then, so we expect more great things to happen in CASP9!
( Posted by
David Baker 127 2544 |
Mon, 06/07/2010 - 21:43 |
3 comments
)
Info for Nature paper
We thought it would be great to include the motivations of Foldit players in our revised submission to Nature. Please help by filling out this quick form (it should take 5-10 seconds).
http://fold.it/portal/node/987789
Thanks,
Zoran
zoran 127 4110 |
Tue, 06/01/2010 - 23:45 |
6 comments
)
Description of updated Alignment Tool!
We have posted to the wiki a detailed description of the newly updated Alignment Tool:
http://foldit.wikia.com/wiki/Alignment_Tool
We hope this will be useful to all of you!
( Posted by beta_helix 127 1431 |
Mon, 05/24/2010 - 03:51 |
3 comments
)
Update to Alignment Tool!
We've posted an update with some features that should make it easier to use the Alignment Tool with multiple templates.
Sequences are now split into two groups, the "working sequences", which you can realign and thread from, essentially as sequences did before. In addition, it is now possible to move sequences in and out
of your "reserve sequences". Reserve sequences are template sequences that are stored outside of the alignment you are working on so you can focus on one (or a few) template(s) at a time. Reserve sequences show up at the bottom of the alignment tool window.
Use the red arrows on the left of each working sequence to move it to the reserve sequences. Use the single green arrow in the bottom left to move a reserve sequence into the working sequences, or the green and red arrow in the bottom left to make a reserve sequence the only working sequence. Use the blue arrows above the reserve sequences to look through them.
The information displayed to the right of each sequence can now be toggled between the alignment score and the name of each sequence, using the button in the top right.
When threading from an alignment, any time a good threading is found, it will be taken and copied over to your protein. Threading will continue looking for better threadings, but you can stop it at any
time, and undo to previous threadings. Threading will still stop on its own when it is done trying threadings.
You can highlight and select sequences on the 3D structure as well as the 2D sequence.
The sequence alignment levels have been moved to be earlier.
(Mon, 05/24/2010 - 01:51 | 0 comments)Developer Preview Update
We've posted an update to the Alignment Tool as a Developer Preview. If you'd like to try it out, please read the FAQ for instructions. The changes are in the release notes.
(Fri, 05/21/2010 - 01:20 | 0 comments)
