R0005 is due next week, so we want to give you the 5 BAKER-ROSETTASERVER predictions (generated using Rosetta@home) before providing you with the top Foldit predictions from Puzzle 508. Resetting the puzzle will cycle through these 5 server models and they are available in the Alignment Tool so you can use partial threading between them.

In electron density puzzles, we give you some experimental data to help you find the correct fold. This data takes the form of an electron density, and appears in game as a guide. You can adjust the guide visualization by going to [Actions]>[Electron Density].

The sixth CASP ROLL target, R0006, is unfortunately another big protein. It is due in less than 3 weeks so again we are starting you off with server predictions. Resetting the puzzle will cycle through 10 different server predictions that are also available in the Alignment Tool so you can use partial threading. The secondary structure predictions are posted in the puzzle comments. If you have trouble loading this puzzle, try checking the box "disable network timeouts" when you login.

This is a Beginner puzzle for new players that have recently completed the Intro Puzzles. The starting model is very far from the correct native structure, can you use the Foldit tools you just learned to fix the model and match the guide? For help with Intro Puzzles, visit http://tinyurl.com/foldit-help . Make sure you have completed the Intro Puzzles (at least up to Level 4-5) before attempting these more difficult Science Puzzles. For players with fewer than 150 global points.

This is a Beginner puzzle for new players that have recently completed the Intro Puzzles. The starting model is very far from the correct native structure, can you use the Foldit tools you just learned to fix the model and match the guide? For help with Intro Puzzles, visit http://tinyurl.com/foldit-help . Make sure you have completed the Intro Puzzles (at least up to Level 4-5) before attempting these more difficult Science Puzzles. For players with fewer than 15 global points.

This puzzle is designed for veteran Foldit players to help new players, so this version of the puzzle is only worth global 50 points.

For the last puzzle for R0001 (which is due next week) we are giving you the 5 BAKER-ROSETTASERVER predictions, generated using Rosetta@home. Resetting the puzzle will cycle through these 5 server models and they are available in the Alignment Tool so you can use partial threading between them.

This puzzle had to be taken down due to a bug with the new Alignment Tool in the developer preview. You can load your solutions from this puzzle into Puzzle 510b.

We want to let you work on the top 5 Foldit predictions for the first CASP ROLL target. We are providing you with early states of those models so that you don't start trapped in local energy minima. Resetting the puzzle will cycle through 5 player predictions that are also available in the Alignment Tool so you can use partial threading. We will then repost this with RosettaServer predictions later this week.

The fifth CASP ROLL target, R0005, is due in 2 weeks so we are skipping the freestyle puzzle and providing you with server predictions. Luckily this is not a big protein and the Alignment Tool has an extended chain that you can work with (if you don't want to be influenced by the server predictions). Resetting the puzzle will cycle through 10 different server predictions. They are also available in the Alignment Tool so you can use partial threading. The secondary structure prediction are posted in the puzzle comments.