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Hold It! Puzzle Update

Hi foldit!

I just wanted to give you guys a warning that we will be ending the Hold It! puzzle a day earlier than expected. You guys have come up with some very interesting solutions already and we wanted to direct more of your hard work towards optimizing one of those designs. We are planning on releasing a replacement puzzle which uses one of your Hold It! puzzle solutions as the starting point. We are also going to apply a few more constraints to make it even MORE fun!

(Tue, 03/09/2010 - 01:39  |  1 comment)

Upgrade complete

The network switch has been swapped out and normal service resumed. Happy Folding!

(Mon, 03/08/2010 - 18:51  |  0 comments)

Upcoming ligand binding puzzle!

Hi Folditeers!!

We have an upcoming Foldit puzzle where we are again attempting to bind a biotin molecule! I hope you all didn't miss it too much! In this puzzle, we have introduced indicators to help the players make more ideal hydrogen bonding angles. For this specific ligand, we're asking for 3 hydrogen bonds to be made with the oxygen at the "business end" of the ligand. (The side that is directed into the scaffold). Here is an example of what the near ideal angles should look like:

We aren't so much interested with hydrogen bonds being made to the linker portions of the ligand. (Everything that is not at the business end of the ligand) But the more the better!

I hope you guys can come up with some interesting solutions! If you can make a good enough solution, we'll make the protein and tell you if it works! (Should take about a month from time of order) And if it works, we'll put you on the resulting paper!

( Posted by  austinday 85 1037  |  Fri, 03/05/2010 - 23:03  |  2 comments )
2

Another small update

We've posted another small update that should improve the in-game rating for recipes.

(Fri, 03/05/2010 - 19:54  |  0 comments)

Scheduled downtime Monday March 8, 6pm GMT

We will be upgrading a network switch. We expect the site to be down for less than an hour, but almost certainly not more. During the downtime, all services (login, scores, chat, etc.) will be unavailable, though if you don't quit the game you will be able to keep on playing.

(Thu, 03/04/2010 - 09:44  |  0 comments)
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