Foldit Standalone Quickstart Guide
Licensing and Downloading
Select "Licence" under "Academic License" and fill out your information.
You will receive an email with instructions to access the download page.
Click on a link to select a numbered release of Rosetta (currently 3.7).
Select the "Foldit Standalone" download link for your platform.
To load in files, choose the "Import PDB/FASTA" button when the program starts. Then select (at least) a ".pdb" or ".fasta" file. The program determines file types by their extension. Depending on the other files you select, different session features will be enabled. For example, selecting a ".density" file will enable electron density.
Here are a few example setups
. For each example, you will need to select all files with the same base filename for import.
example_pdb - basic PDB
example_fasta - basic FASTA
example_guide - includes a guide structure
example_density - includes electron density; enables the electron density panel
example_template - includes a template; enables the alignment panel
example_ligand - includes a ligand as a custom residue type
example_dna - includes DNA
example_rna - includes RNA
Here are some example Rosetta Script files: repack_no_design.xml
(these may take up to a minute or two to complete).
Help and Troubleshooting
Please download the latest version from the licencing site above.
Reference sheet with useful key commands and other tips.
If you are on macOS, please make sure to move the FolditStandalone.app to your /Applications folder before running.
If you are on macOS and get a message about the application being from an unknown developer when you try to launch it, try right-clicking on the application and selecting "Open".
If you are encountering trouble, you may find more information in the log file. It can be found at:
Linux: [working directory]/log.txt
If you are having issues importing files during an existing session, try restarting the program and importing them from the starting screen.
If you are having issues importing a large number of different file types, try a setup with fewer file types.
UserEcho site for feedback.